Halothane and Liver Dysfunction: a Retrospective Study
نویسندگان
چکیده
منابع مشابه
Halothane and liver damage.
The Medical Assessor to the Committee on Safety ofMedicines recently issued' a letter entitled "Jaundice following repeated exposure to halothane," in which he noted that 130 reports of jaundice following anaesthesia had been received by the committee between 1964 and 1972, every case being associated with the use of halothane. Ninety-four of these patients had been exposed to halothane more th...
متن کاملHalothane and liver damage.
Halothane was first synthesized by Suckling in 1952 and introduced into clinical practice a few years later.',2 Its many advantages, such as quick action, easy administration, non-explosiveness, high potency and low cost, led to its widespread use within a short time. Although initial animal work did not indicate any hepatotoxic effect,3`5 the first cases of unexplained hepatitis after exposure...
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Background: Halothane is the routine used inhalation anesthetic drug in the world but at present, there is an increasing interest for using intravenous anesthetics like propofol. The purpose of this study was to compare these anesthetic effects on hepatic enzymes.Methods: From 2006 to 2007, this study was performed on fifty eight patients classified in class I of American Society of Anesthetics...
متن کاملHalothane anaesthesia and liver damage.
A recent experience of the senior author when addressing a meeting of anaesthetists prompted this review, since it was apparent that there was still considerable disagreement between hepatologists and anaesthetists over the association between liver cell damage and halothane anaesthesia and the measures by which the risk could be minimised. Although during the 1960s and 1970s the evidence was h...
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Hyaluronic acid (HA), laminin (LN), amino-terminal pro-peptide of type III pro-collagen (PIIINP), and collagen IV (CIV) are four major serum markers of liver fibrosis. This retrospective cross-sectional study aimed to evaluate the correlations of the four serum markers with the severity of liver dysfunction in cirrhotic patients. Between January 2013 and June 2014, a total of 228 patients with ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1964
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5405.329